Why can coffee refresh caffeine and the principle of refreshing? why do you want to go to the bathroom after drinking coffee?

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What is the mechanism for eliminating drowsiness through caffeine?

We all know that the caffeine contained in coffee or refreshing drinks has a refreshing and sleepy effect. Here, on the premise that caffeine can suppress drowsiness, teach some ways to make good use of caffeine.

One of the key points is that caffeine blocks an inhibitory neurotransmitter called Adenosine. The most representative effects of adenosine are as follows:

The original role of adenosine

In order to block the effect of adenosine...

The role of ① in promoting sleep

The effect of ② on reducing heartbeat and pulse velocity

The pain-inducing effect of ③

The effect of ④ on promoting Blood Circulation

The effect of ⑤ on renal blood flow velocity

Caffeine intake

→ suppresses drowsiness

→ increases heartbeat and pulse speed

→ relieves pain

→ relaxes blood circulation

→ is easy to urinate.

First of all, caffeine can block the "sleep-promoting effect of ①" of adenosine and have a waking effect. Caffeine itself is not a refreshing substance. In other words, the principle of "caffeine intake" is to artificially block naturally occurring drowsiness through caffeine. The function of caffeine is to deceive the brain from paying attention to the naturally occurring drowsiness.

Drinking only two or three cups of coffee won't make much difference, but if caffeine overintake persists chronically, it can cause the brain to lose its wakefulness and sleep rhythm. Natural drowsiness no longer comes at a natural time and may lead to insomnia.

To prevent this from happening, here are several key points for caffeine intake.

It is better to choose hot coffee than iced coffee

First of all, do you know which kind of caffeine has a faster effect than hot coffee or iced coffee? The answer is hot coffee. The low temperature of iced coffee can cause small intestinal mucosa and capillaries to contract, delaying the body's absorption of caffeine. At the same time, the concentration of caffeine in iced coffee rises a little slower than that in hot coffee. If you want caffeine to work as soon as possible, it is recommended to drink hot coffee.

Three cups of coffee at nine o'clock, 12:00 and three o'clock in the afternoon is the strongest caffeine strategy.

In addition, the effect of caffeine in the blood weakens, that is, the time it takes to reduce the concentration to only half of the highest value (half-life), which is about two and a half hours to four and a half hours in the case of healthy adults. However, the half-life also varies with age and physical condition, with young and healthy people an hour or two earlier, and older people with a later absorption rate of about four to five hours.

From the above, it can be seen that instead of drinking coffee one after another, it is better to wait until the blood concentration of caffeine decreases, which is the most efficient way to get caffeine.

By the way, what is the reason why caffeine intake makes people urinate frequently?

Urine is made by the kidneys, and one of the aforementioned effects of adenosine, the effect of ⑤ on kidney blood flow, is inhibited by caffeine intake, resulting in an increase in blood flow to the kidneys. The blood keeps flowing to the kidneys, and the kidneys continue to produce new urine, causing frequent urination.

In other words, caffeine intake before bedtime not only blocks drowsiness, but also increases the frequency of getting up and going to the toilet after falling asleep, which further lowers the quality of sleep.

At the same time, caffeine can also promote intestinal peristalsis, which can easily cause abdominal pain and diarrhea. People with bad intestines and stomach had better avoid excessive caffeine intake.

You may have heard the saying that caffeine has a "cardiotonic effect". This is related to one of the effects of adenosine, "the effect of ② on heart rate", which is inhibited after caffeine intake and the heartbeat accelerates. Under the influence of this cardiotonic effect, the heart beat faster, vasoconstriction, and blood pressure may also rise. Some people who drink too much coffee have heart palpitations because of the cardiotonic effect of caffeine.

People who suffer from panic attacks, anxiety disorders and nervous disorders are likely to cause palpitations and rapid heartbeats if they accidentally ingest too much caffeine.