Coffee research caffeine is generally not poisoned.

Throughout human history, there are only a few cases of caffeine poisoning. If we consider that a large number of people around the world drink coffee and other drinks (cola, tea, etc.), then cases of coffee poisoning are extremely rare in the world medical literature. This substance is very safe for ordinary consumers. The dose that causes adult death is about 5-10 grams of caffeine, which is equivalent to more than 100 cups of coffee.

However, lower doses can also cause poisoning symptoms, about 1 gram, which is equivalent to drinking 20-50 cups of coffee, and some people who are not used to drinking coffee every day will react immediately. Some people are highly tolerant because they drink coffee every day and become poisoned only after drinking a large amount of coffee. The main symptoms occur in the central nervous system and cardiovascular system. Insomnia, restlessness and increased excitability are the initial manifestations, with people feeling unable to sleep, restlessness, discomfort and anxiety, followed by tachycardia, tinnitus and dizziness. Muscle tension, palpitations, etc. With the increase of the dose, there will be vomiting, spasms, coma and even death. Some people may die of shock or pulmonary edema with atelectasis or cardiac arrest. Children are more resistant to caffeine, and although high intake can lead to toxic symptoms, no deaths have been reported.