Why is coffee refreshing? The principle of coffee refreshing why some people do not drink coffee refreshing?
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Everyone knows that the pick-me-up effect of drinking coffee for a long time will gradually lose, but do you know? Some people are born without the refreshing effect of coffee, and even refreshing drinks with extremely high caffeine, such as Bull, can not be effectively refreshed. What's going on? In fact, the so-called pick-me-up effect is not very accurate. Caffeine is refreshing because it shuts down the drowsiness switch in the brain.
There is a receptor in the brain that makes the brain feel sleepy. This receptor is regulated by adenosine, and when adenosine binds to it, people feel sleepy. Because caffeine is similar to adenosine, the receptor that controls drowsiness binds to caffeine; this "wrong binding" doesn't make the brain feel sleepy, so people don't want to sleep.
Some people's brain receptors that control drowsiness are different from others and are less likely to bind to caffeine, making them less refreshing when drinking coffee.
Those who drink coffee do not have a refreshing effect because the receptors that control drowsiness in their brains are "too smart" to be deceived by caffeine, so they can dutifully put their hosts to sleep at the right time. This is actually more beneficial to health, because caffeine does not relieve fatigue, it just makes tired people unable to feel sleepy, but what is owed will always be repaid, and fatigue that has not been resolved through sleep will eventually be recovered in the future. like disrupting the biological clock. In fact, caffeine is refreshing in part because it affects the biological clock.
Why can people in Europe and America drink so much coffee?
People in Europe and the United States generally drink more cups of coffee than Asians, which has nothing to do with the adenosine receptors that control drowsiness, but their livers can metabolize caffeine more than Asians, so caffeine has less effect on their bodies. Naturally, you can drink a few more cups of coffee than Asians.
Whether caffeine works effectively is not only related to adenosine receptors in the brain, but also to the ability of the liver to metabolize caffeine and the operation of the physiological clock. For example, a substance called cortisol and other substances such as melatonin regulate the physiological clock. Cortisol awakens the brain, and cortisol has the highest concentration when you wake up in the morning, so drinking coffee when you wake up is superfluous, because cortisol produced by the body has a refreshing effect. Therefore, experts will advise people not to drink coffee early in the morning, so as not to waste the benefits of coffee, but may consume too much caffeine.
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