The key to reducing the risk of Parkinson's disease by drinking coffee lies in genes.
Dr. Dr. Haydeh Payami of the New York State Department of Health reported on September 29 at the World Parkinson's Congress (World Parkinson Congress) in Glasgow, England, that researchers have found a gene called GRIN2A, which stimulates the protective effect of caffeine in people, so drinking coffee reduces the risk of Parkinson's disease. This also explains why some experimental drugs have no effect on Parkinson's patients in clinical trials, and the pharmaceutical industry is expected to use this discovery to develop experimental drugs against Parkinson's disease.
A team led by Dr. Hyde-Payami studied 4, 000 volunteers, half of whom had Parkinson's disease, scanned the subjects' genomes with a "ILLUMINA" gene chip, conducted a "whole-genome association study" and investigated the subjects' daily coffee drinking habits, and found that the GRIN2A gene stimulates caffeine, thereby reducing the risk of Parkinson's disease. 1/4 of the world's population carries the GRIN2A gene.
GRIN2A is associated with a compound called glutamate (glutamate), which is suspected of killing brain cells in people with Parkinson's disease. Glutamate is affected by another compound, adenosine (adenosine), and coffee interferes with this process. This explains why the "A2A adenylate receptor antagonist", which has been used in clinical trials of Parkinson's disease and other neurological diseases, does not work well. The key lies in the GRIN2A gene, which can only be effective in patients with the GRIN2A gene.
The medical community has long known that some people drink coffee to prevent Parkinson's disease, but the cause has not been understood. Now the answer is: it has something to do with genes. The discovery is of great significance for the development of drugs for Parkinson's disease.
- Prev
Research shows that drinking more brewed coffee can reduce the risk of breast cancer
Drinking more Scandinavian brewed coffee (similar to French kettle and Turkish / Greek pot brewed coffee) can reduce women's risk of breast cancer, according to a new study released by the University of Meau in northern Sweden.
- Next
People who drink a lot of coffee have a lower risk of prostate cancer
Compared with non-drinkers, people who drank six or more cups of coffee a day had a nearly 20% lower risk of prostate cancer over the past 20 years, the researchers found. Scientists at Harvard University followed 47911 men who regularly reported their coffee consumption. More importantly, compared with non-coffee drinkers, people who drink a lot of coffee suffer from fatal prostate disease.
Related
- The coffee industry is huge! Coca-Cola wants to sell Costa at a low price of 25%?!
- The memories are gone! Shenzhen's last Man Coffee shop is permanently closed!
- What are the characteristics of hand-brewed coffee? How to use the Rao Spin coffee brewing method? Europe and North America share their hand-charging methods!
- How to choose the direction of the circulation of hand-brewed coffee? Should I fill the water clockwise or counterclockwise when making coffee by hand? How do you turn around while making coffee?
- What is the ratio of water to coffee in American coffee? What beans are the best for American coffee? What is the best espresso for American coffee?
- Affected more than 40 cities! Starbucks employees launch an indefinite strike!
- Fortunately, employees disclosed the new black tea latte! Netizen: Replace the short extract
- The flavor difference between hand-brewed coffee at high temperature, medium temperature and low temperature can coffee be heated again
- The difference between single coffee and SOE Why are soe coffee beans more expensive? Soe acid or not
- Fruit porridge?! Chabaidao launches "Solid Poplar Branch Ganlu"