Coffee helps to treat Alzheimer's disease!

This is an attractive concept that our daily pick-me-up also gives us a range of health benefits. And for coffee drinkers, there is a lot of research on water seepage. Some studies have shown that daily caffeine habits can help prevent Alzheimer's disease. But there is one problem. For a cup or two days, it doesn't seem to be enough for most Americans. Researchers say 500 milligrams of caffeine, about five cups of regular coffee, is a dose that seems to protect the brain.

A day of five cups

It sounds like a caffeine overdose. After five cups, many people will end up with unease and make an extra trip to the toilet. But the hard core of some coffee lovers:

"I drink five to six drinks a day for religion," said Gary Arendash, a researcher at the Alzheimer's Research Center in Florida, part of Florida State University. Arendash says he thinks caffeine protects his brain.

Arendash and his colleagues at the Alzheimer's Research Center in Florida have been studying the effects of caffeine on the brains of mice with Alzheimer's disease. They have found that the eating habits of rodents can lead to great progress by adding caffeinated water. The mice did better on short-term memory and thought tests. But only if they get enough caffeine.

"equivalent to two or three cups of coffee in humans, there is no benefit in our Alzheimer's mice," Arendash said.

Arendash's team also demonstrated that these super-caffeinated mice ended up with abnormal amyloid, which is thought to play an important role in the development of Alzheimer's disease by about 50%.

About a cup of coffee for a day and a half of a typical American drink. "so as you can see, many of us are below the threshold level that we think gives protection benefits," Arendash said.

The evidence is inconclusive.

The study of caffeine in Alzheimer's mice is interesting for researchers who try to translate the results into recommendations. But explaining animal research can be tricky.

"it's always a good place to start," says Joan Lindsey of the University of Ottawa. "but we never know how and how it will prop up humans." After all, people are much more complicated. Researchers already know that mice can respond to changes in drugs, environmental toxins or nutrients that are really different from humans.

Another challenge is to find a reliable test of the mouse's memory. Arendash used a mouse maze to assess the spatial memory of his Alzheimer's mice. He put the rats in the small pool with many alleys and dead ends to see how they could quickly find and remember the hidden escape platform. Similar human studies used in computer-based maze tests.

"that's the first thing to lose in Alzheimer's is short-term memory-memory of what happened a few seconds or a minute ago," Arendash said. "this is where [the water maze] is focused."

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Observe the coffee hobby of middle-aged villagers

There won't be as much benefit as possible in the Arendash mouse study, if scientists haven't begun to gather some evidence that a stable caffeine habit is beneficial in humans, too.

In a recent study, researchers from Finland followed about 1400 people there to drink coffee for more than two decades. The researchers found that a group seemed to benefit the most: people who had been drinking coffee three to five cups a day in their 40s and 50s.

"they have a 65 to 70 percent lower risk of developing Alzheimer's disease at the age of 70," said Huntington Porter, a neurobiologist at the University of South Florida. Ceramists say it works, even if researchers control things, such as cardiovascular disease, that can affect the risk of Alzheimer's disease.

Other smaller studies in Europe have led to similar results, but experts say the study only establishes a relationship between coffee consumption and brain protection.

"I would not hesitate to say that there is epidemiological evidence that coffee can prevent Alzheimer's disease," said Reisa Sperling, an Alzheimer's researcher at Brigham Women's Hospital at Harvard University.

It is possible that these regular coffee drinkers may have common habits and so on, which can explain the protective effect. "people who are very active in middle age are more likely to drink coffee than couch potatoes," Sperling said. Perhaps coffee drinkers will not benefit as much from coffee as they are from maintaining their mental and physical activities. These studies make it difficult for Seuss to come out.

Drinking coffee does not offset genetic risk

Sperling says Alzheimer's is an incredibly complex disease. Exercise and good nutrition seem to be protective, but a person's risk is largely determined by genes. No change in behavior or eating habits-like drinking coffee-can eliminate this risk.

If future research brings stronger evidence that caffeine may pass through some small proportions, this means that coffee lovers will have a greater risk of drinking away modifications.

Just make sure those five cups don't keep you all night.-Sleep is an important health guarantee.