The struggle between Coffee and Alzheimer

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Why is Alzheimer's disease called Alzheimer's disease?

Eros Azheimer (1864.6.14-1915.12.19) was a German psychiatrist. In 1906, German doctor Alois Alzheimer (Alois Alzheimer) received a brain specimen from a woman who had just died. It was against this background that Alzheimer fixed, stained, sliced and placed the patient's brain sample under a microscope. What is surprising and unusual is the pathological features: Brown plaques can be seen everywhere in the cerebral cortex, and the surface of these patches are covered with short, curved lines, as if a piece of iron magnet is cluttered with pins. At the same time, wool-like fibers fill the interior of nerve cells like weeds. Later, people realized that it was these distinctive pathological tissues that prevented normal communication between nerve cells, causing a large number of nerve cell death, brain atrophy, and eventually leading to Alzheimer's disease. He first published a case of Alzheimer's disease, which was later named Alzheimer's disease.

Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly, and the incidence increases with age. The prevalence rate is about 5% over 65 years old and 20% over 85 years old. The prevalence rate of women is 3 times higher than that of men.

The Mechanism of the struggle between Coffee and Alzheimer

Alzheimer's disease is a neurodegenerative disease, which is characterized by amyloid plaque in brain tissue sections, gradual death of neurons, impairment of cognitive and memory ability, and gradual loss of independent living ability. finally, the brain function is seriously damaged until death.

Previous studies have found that long-term regular consumption of moderate amounts of coffee can reduce the incidence of Alzheimer's disease by up to 20%. In fact, the idea that caffeine helps restore memory impairment in older mice with Alzheimer's disease was first discovered by the ADRC team in Florida. "this new finding provides evidence that caffeine may treat Alzheimer's disease, not just protect it," said lead author Gary W Arendash, a neurologist at ADRC, Florida. "caffeine is a safe anesthetic for most people and is easy to get into the brain, which is very important and has a direct effect on the course of the disease."